The TyG index was a good discriminant of MS. The cut-off point for the TyG index was 8.8 in men and 8.7 in women the respective values for TG/C-HDL were 3.1 in men and 2.2 in women. The positive likelihood ratios and post-test probabilities for these parameters were 5.8 vs 3.1 and 72% vs 58% respectively. The cut-off values for MS in the overall population were 8.8 for the TyG index (sensitivity = 79%, specificity = 86%), and 2.4 for the TG/HDL-C ratio (sensitivity = 88%, specificity = 72%). The mean value of the TyG index was higher in the group with MS as compared to the group without MS and its correlation with the TG/HDL-C ratio was good. The discriminating capacities for MS of the TyG index, calculated as Ln (TG × glucose /2), and the TG/HDL-C ratio were evaluated. Materials and methodsĪn observational, cross-sectional study was conducted on 525 adults of a population from Bahia Blanca, Argentina, who were divided into two groups: with MS (n = 89) and without MS (n = 436). The aim of this study was to evaluate the triglycerides and glucose (TyG) index as a marker of insulin resistance and to compare it to the triglycerides/HDL cholesterol ratio (TG/HDL-C), in subjects with and without metabolic syndrome (MS). Therefore, different estimators for this condition have been suggested. For a very high triglyceride level, your doctor can prescribe a high-dose omega-3 medication.Insulin resistance assessment requires sophisticated methodology of difficult application. The omega-3 fats in fish and fish oil capsules are another triglyceride-lowering option. Depending on the dose, statins can lower triglycerides by 20%–40%. If you're taking a statin to lower your LDL, one side benefit may be reduced triglyceride levels. How to lower triglyceride levels with medication Your doctor will advise you of measures you can take to lower high triglycerides. Many of the steps you should take to lower triglycerides are the same ones you should take to protect your heart and health overall. An underactive thyroid (hypothyroidism).What causes high triglyceride levels?įactors that can raise your triglyceride level include: People can have "isolated" high triglycerides without low HDL levels, and research is now showing that high triglycerides are an independent risk factor for cardiovascular disease, no matter what the HDL is. Triglycerides and HDL are metabolically connected and are often inversely related: As triglycerides go up, HDL tends to go down - and vice versa. For metabolic syndrome, that group includes abdominal obesity (as measured by waistline), high blood pressure, high blood sugar, low HDL cholesterol - and, yes, high triglyceride levels. The risk of eventually developing diabetes is even greater.Ī syndrome is, by definition, a group of signs and symptoms that occur together because of an underlying condition. People with metabolic syndrome are several times more likely to have a heart attack or stroke. Triglycerides can be one of the signs of metabolic syndrome, which increases the risk for having a heart attack or stroke. Source: National Cholesterol Education Program. What level of triglycerides is dangerous?īut what about treating lower levels of triglycerides? Recent evidence suggests you should work to reduce triglyceride levels if they are higher than normal, especially if you have heart disease or have other risk factors such as diabetes, high blood pressure or smoking. There's no question that extremely high levels (1,000 mg/dL or more) spell trouble and can lead to acute pancreatitis. Until recently, triglycerides tended to get less attention when looking at cardiovascular risk compared to LDL and HDL cholesterol levels. However, high triglycerides in your blood is linked to a higher risk of heart disease and stroke. Your body makes triglycerides or gets them from the foods you eat. Triglycerides are a type of fat that gets stored in adipose tissue and circulates in blood.
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